Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444885 | 0.86 | PTGER4 (0.52) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL4446913 | 0.85 | CA1 (0.56) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6097301 | 0.84 | POLB (0.50) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6095627 | 0.84 | CA12 (0.59) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6096752 | 0.82 | CA1 (0.54) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6096713 | 0.82 | CA1 (0.52) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6097730 | 0.81 | PTGER4 (0.53) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6097860 | 0.81 | CA12 (0.55) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6098289 | 0.81 | PTGER4 (0.51) | PTGER4CA12CA1CA9CA2 | |
| SCHEMBL6097324 | 0.81 | CA1 (0.54) | PTGER4CA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | claimed |