⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350595 | 0.93 | CYP2C19 (0.31) | — | |
| SCHEMBL6147874 | 0.81 | — | — | |
| SCHEMBL27925257 | 0.74 | — | — | |
| SCHEMBL174397 | 0.70 | FFAR3 (0.32) | — | |
| SCHEMBL2772996 | 0.70 | FFAR3 (0.32) | — | |
| SCHEMBL15571664 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL2198959 | 0.68 | FFAR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4359360 | 0.68 | FFAR3 (0.31) | — | |
| SCHEMBL28113416 | 0.67 | FFAR3 (0.31) | — | |
| SCHEMBL28327359 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310732-B1 | PROCESS FOR THE PREPARATION OF N-ACYL-N-ALKYL-2,6-DIALKYL-3-CHLOROANILINES | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | claimed |
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | claimed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| WO-2006090268-A2 | PROCESSES FOR THE PREPARATION OF ALFUZOSIN AND SALTS THEREOF AND NOVEL CRYSTALLINE FORMS OF ALFUZOSIN | GLENMARK PHARMACEUTICALS LIMITED (US) | 2006-08-31 | — | — | WO | disclosed |
| US-5959108-A | SUSPENDING AND HEAT TREATING A CRYSTALLINE ADDUCT OF TERAZOSINE HYDROCHLORIDE AND METHANOL IN A POLAR SOLVENT OF A LOW-MOLECULAR-WEIGHT ALCOHOL OR KETONE; SEPARATING THE CRYSTAL FORM IV; REDUCED HYGROSCOPICITY AND SOLVENT RETENTION | CU CHEMIE UETIKON GMBH (DE) | 1999-09-28 | — | — | US | disclosed |
| US-4772309-A | 5-acylamino-pyrazoles, composition containing them, and herbicidal and plant growth regulating method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4199588-A | TRANQUILIZERS, MUSCLE RELAXANTS, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-04-22 | — | — | US | disclosed |
| US-4100288-A | N-Tetrahydrofurfuryl-noroxymorphones, their salts, and analgesic compositions and methods employing them | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-11 | — | — | US | disclosed |
| US-4087532-A | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-02 | — | — | US | disclosed |