SCHEMBL6113446

SCHEMBL6113446

CC(C)CNc1nc2cc(F)c(F)cc2n2c(-c3ccc(C(=O)NC4CC4)c(Cl)c3)cnc12.Cn1cc(CNc2nc3cc(F)c(F)cc3n3c(-c4ccc(C(=O)NC5CC5)c(Cl)c4)cnc23)cn1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TTK P33981 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121186 0.95 TTK (0.52) TTK
SCHEMBL3730057 0.92 TTK (0.62) TTK
SCHEMBL6113294 0.88 TTK (0.52) TTK
SCHEMBL122816 0.88 TTK (0.53) TTK
SCHEMBL6113529 0.86 TTK (0.48) TTK
SCHEMBL13077036 0.85 TTK (0.52) TTK
SCHEMBL175937 0.85 TTK (0.49) TTK
SCHEMBL121160 0.85 TTK (0.48) TTK
SCHEMBL3808559 0.84 TTK (0.63) TTK
SCHEMBL120899 0.84 TTK (0.51) TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120128662-A1 SUBSTITUTED IMIDAZOQUINOXALINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-05-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128662-A1 SUBSTITUTED IMIDAZOQUINOXALINES TTBK1, TTK, TTBK2 TTK 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.