Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118869 | 0.92 | SCN5A (0.51) | SCN5ATDP1MEN1KMT2APDE4A | |
| Hydrochloric Acid SCHEMBL6118997 | 0.91 | SCN5A (0.50) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6118353 | 0.90 | MAPK14 (0.53) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6118927 | 0.90 | SCN5A (0.49) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6118393 | 0.90 | SCN5A (0.49) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6118125 | 0.90 | SCN5A (0.49) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6118604 | 0.90 | KDM4E (0.54) | SCN5ATDP1MEN1KMT2APDE4A | |
| SCHEMBL6119042 | 0.90 | SCN5A (0.53) | SCN5ATDP1MEN1KMT2APDE4A | |
| Hydrochloric Acid SCHEMBL6118909 | 0.89 | SCN5A (0.48) | SCN5ATDP1MEN1KMT2APDE4A | |
| Hydrochloric Acid SCHEMBL6119048 | 0.89 | SCN5A (0.48) | SCN5ATDP1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199983-B2 | 3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof | CAI SUIXIONG (CN) | 2015-12-01 | — | — | US | claimed |
| WO-2012065297-A1 | 3-ARYL-6-ARYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF | IMPACT THERAPEUTICS, INC. (CN) | 2012-05-24 | — | — | WO | claimed |
| US-9199983-B2 | 3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof | CAI SUIXIONG (CN) | 2015-12-01 | — | — | US | disclosed |
| WO-2012065297-A1 | 3-ARYL-6-ARYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF | IMPACT THERAPEUTICS, INC. (CN) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012065546-A1 | 3-ARYL-6-ARYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF | IMPACT THERAPEUTICS, INC. (CN) | 2012-05-24 | — | — | WO | disclosed |