Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.71 |
| ▸ | P4HB | P07237 | 5/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | XDH | P47989 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.71 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CA12 | O43570 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CA4 | P22748 | 2/20 | 0.71 |
| ▸ | CA7 | P43166 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALPI | P09923 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Reynoutrin SCHEMBL31130799 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL20298285 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL38138 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Guajaverin SCHEMBL3635416 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL5590747 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL14350762 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL3641504 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL6759025 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL4226891 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA | |
| Reynoutrin SCHEMBL28550462 | 1.00 | KDM4E (0.71) | KDM4EAKR1B1P4HBEPHX2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108619245-B | New application of guava leaves and total flavonoids in guava leaves | 天津市医药科学研究所 | 2021-08-27 | — | — | CN | disclosed |
| US-20200120909-A1 | COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY | THE JOHNS HOPKINS UNIVERSITY | 2020-04-23 | — | — | US | disclosed |
| EP-2878197-B1 | TISSUE PRESERVATION SOLUTION AND TISSUE PRESERVATION METHOD | UNIV OSAKA (JP) | 2018-12-26 | — | — | EP | disclosed |
| US-20160120158-A1 | COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY | UNIV JOHNS HOPKINS (US) | 2016-05-05 | — | — | US | disclosed |
| US-20150351380-A1 | TISSUE-PRESERVING LIQUID AND TISSUE-PRESERVING METHOD | OSAKA UNIVERSITY (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2878197-A1 | TISSUE-PRESERVING LIQUID AND TISSUE-PRESERVING METHOD | Osaka University (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-20140080795-A1 | NRF2 Deficiency Influences Susceptibility to Steroid Resistance via HDAC2 Reduction | UNIVERSITY OF ROCHESTER (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2012068454-A2 | NRF2 DEFICIENCY INFLUENCES SUSCEPTIBILITY TO STEROID RESISTANCE VIA HDAC2 REDUCTION | UNIVERSITY OF ROCHESTER (US) | 2012-05-24 | — | — | WO | disclosed |