Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947130 | 0.86 | TSHR (0.38) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL8711766 | 0.83 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL357591 | 0.81 | TSHR (0.40) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL13392800 | 0.81 | SLC1A3 (0.41) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL8419732 | 0.81 | TSHR (0.45) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL28797022 | 0.81 | MEN1 (0.45) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL357592 | 0.81 | TSHR (0.40) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL8709152 | 0.80 | TSHR (0.33) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL6811532 | 0.80 | TSHR (0.33) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL11447748 | 0.80 | CA1 (0.50) | TSHRSLC1A1MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |
| US-5731395-A | POLYMER CONTAINING DIVINYLBENZENE AND STYRENE COMPOUND | ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |