Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27646037 | 0.98 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| Hydrochloric Acid SCHEMBL28763000 | 0.98 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| Ammonia Solution, Strong SCHEMBL6807094 | 0.98 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| Bromide SCHEMBL28241790 | 0.98 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| Hydrochloric Acid SCHEMBL5973455 | 0.96 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7549979 | 0.92 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL27926441 | 0.90 | TDP1 (0.51) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7242914 | 0.90 | TDP1 (0.51) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL15244383 | 0.89 | TDP1 (0.50) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3341020 | 0.88 | TDP1 (0.67) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 866 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879780-B | Preparation method of (2-methylamine-ethyl) -tert-butyl carbamate | 上海卡洛化学有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-110981803-A | Anti-tumor compound and synthesis method and application thereof | 北京大学 | 2020-04-10 | — | — | CN | claimed |
| CN-102216279-B | Phenyl pyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof | TOPHARMAN SHANGHAI Co.,Ltd. (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103201267-A | AMPK-activating heterocyclic compounds and methods of use thereof | RIGEL PHARMACEUTICALS INC | 2013-07-10 | — | — | CN | claimed |
| CN-101910131-A | Carboxamide, sulfonamide and amine compounds for metabolic disorders | RIGEL PHARMACEUTICALS INC | 2010-12-08 | — | — | CN | claimed |
| CN-101747282-A | Phenyl pyrimidone compounds, pharmaceutical compositions and preparation methods and uses thereof | TOPHARMAN SHANGHAI CO LTD | 2010-06-23 | — | — | CN | claimed |
| CN-101559053-A | 5-membered heterocycle derivatives, production thereof and use thereof as medicaments | SOD CONSEILS RECH APPLIC (FR) | 2009-10-21 | — | — | CN | claimed |
| CN-101311174-A | Vitamin B6 derivates and pharmaceutical use thereof | FANG WU (CN) | 2008-11-26 | — | — | CN | claimed |
| CN-100425600-C | Benzothiazole-and benzo \\58743, oxazole-4, 7-dione derivatives and their use as CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2008-10-15 | — | — | CN | claimed |
| CN-1257174-C | Producing process for N-[3-(tert-butyl oxycarbonyl amino) propy1]-2-amino ethylphosphonic acid diallcylester | WYETH CORP (US) | 2006-05-24 | — | — | CN | claimed |
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| CN-1468226-A | Biphenyl derivatives and their use as ppar-gamma receptor activators | �������о�����չ˽������˾ | 2004-01-14 | — | — | CN | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| CN-1345308-A | Acetylenic alpha-amino acid based sulfonamide hydroxamic acid TACE inhibitors | AMERICAN CYANAMID CO (US) | 2002-04-17 | — | — | CN | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| CN-1265664-A | Preparation method of [ 2- ((8,9) -dioxo-2, 6-diazabicyclo [5.2.0] -non-1 (7) -en-2-yl ] ethyl phosphonic acid | AMERICAN HOME PROD (US) | 2000-09-06 | — | — | CN | claimed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | claimed |
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | claimed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | claimed |