Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706658 | 1.00 | NAMPT (1.00) | NAMPT | |
| SCHEMBL6121583 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3703491 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3711231 | 0.87 | NAMPT (1.00) | NAMPT | |
| SCHEMBL6120688 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3711241 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL6121966 | 0.83 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3702795 | 0.83 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3706125 | 0.79 | NAMPT (1.00) | NAMPT | |
| SCHEMBL6122638 | 0.79 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640698-A1 | NAMPT AND ROCK INHIBITORS | AbbVie Inc. (US) | 2013-09-25 | — | — | EP | claimed |
| WO-2012067965-A1 | NAMPT AND ROCK INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | claimed |
| EP-2640698-A1 | NAMPT AND ROCK INHIBITORS | AbbVie Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067965-A1 | NAMPT AND ROCK INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | disclosed |