SCHEMBL61225

SCHEMBL61225

C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@@H]12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.68
PAX8 Q06710 3/20 0.68
RAB9A P51151 3/20 0.68
LMNA P02545 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
HIF1A Q16665 2/20 0.68
NPC1 O15118 2/20 0.68
CYP3A4 P08684 1/20 0.68
TSHR P16473 1/20 0.68
ATP1A1 P05023 1/20 0.68
ATP1B1 P05026 1/20 0.68
ATP1A3 P13637 1/20 0.68
ATP1B2 P14415 1/20 0.68
ATP1A2 P50993 1/20 0.68
ATP12A P54707 1/20 0.68
ATP1B3 P54709 1/20 0.68
FXYD2 P54710 1/20 0.68
ATP1A4 Q13733 1/20 0.68
CYP2C19 P33261 2/20 0.64
HSD17B10 Q99714 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307864 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL21578272 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL11654361 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL4905392 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL7309200 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL8999665 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL11806297 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL7279420 1.00 TP53 (0.68) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL8830696 0.89 TP53 (0.56) TP53PAX8RAB9ALMNASMN1; SMN2
SCHEMBL8830484 0.89 TP53 (0.56) TP53PAX8RAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2195 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137707-A1 METHODS OF MODULATING ATXN2 EXPRESSION UNIV OF UTAH RESEARCH FOUNDATION (US) 2026-05-21 US claimed
WO-2025151443-A1 ENDOXIFEN FOR TREATMENT OF RARE CANCERS ATOSSA THERAPEUTICS, INC. (US) 2025-07-17 WO claimed
EP-4536236-A2 METHODS OF MODULATING ATXN2 EXPRESSION University of Utah Research Foundation (US) 2025-04-16 EP claimed
US-12097234-B2 Extract containing oleandrin and method of production thereof PHOENIX BIOTECHNOLOGY, INC. (US) 2024-09-24 US claimed
US-20240293551-A1 USE OF ST-TYPE LIPID COMPOUNDS IN PREPARATION OF NUCLEIC ACID DELIVERY REAGENT AND RELATED PRODUCT BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2024-09-05 US claimed
US-20240261312-A1 Method and compositions for treating animal viral infections PHOENIX BIOTECHNOLOGY, INC. (US) 2024-08-08 US claimed
EP-4378483-A1 USE OF ST-TYPE LIPID COMPOUNDS IN PREPARATION OF NUCLEIC ACID DELIVERY REAGENT AND RELATED PRODUCT Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CN) 2024-06-05 EP claimed
CN-118103046-A Methods and compositions for treating viral infections in animals 菲尼克斯生物技术公司 2024-05-28 CN claimed
EP-4333851-A1 CORRECTION OF EXON SKIPPING IN MONOCYTE-DERIVED CELLS FOR IMPROVED IMMUNE RESPONSE Schelling, D. Christopher (US) 2024-03-13 EP claimed
WO-2024028324-A1 MOLECULES FOR THE PREVENTION AND TREATMENT OF NEUROMUSCULAR DISORDERS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2024-02-08 WO claimed
EP-0003456-B1 3-AMINO-CARDENOLIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM ETABLISSEMENTS NATIVELLE S.A. (FR) 1984-11-07 EP claimed
EP-0078495-A1 Process for the preparation of digitoxigenin HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
EP-0027023-A1 Furyl intermediates of cardenolides, their synthesis and production of cardenolides and their isomers therefrom Advance Biofactures Corporation (US) 1981-04-15 EP claimed
US-4259240-A Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom ADVANCE BIOFACTURES CORPORATION (US) 1981-03-31 US claimed
US-4230621-A TRACERS, HYDROXYPHENYLGLUTARIC ACID DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1980-10-28 US claimed
US-4064227-A Radioimmunoassay method for the determination of cardiotonic glycosides MALLINCKRODT, INC. (US) 1977-12-20 US claimed
US-4060607-A Cardenolide derivatives ETABLISSEMENTS NATIVELLE S.A. (FR) 1977-11-29 US claimed
US-4011212-A 22-CYANO-24-NORCHOLANES AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-08 US claimed
US-3944541-A 22-Cyano-24-norcholanes AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-16 US claimed
US-3933791-A Obtention of digitoxigenin from neriifolin and 2'-acetylneriifolin SYNTEX (U.S.A.) INC. (US) 1976-01-20 US claimed