SCHEMBL612290

SCHEMBL612290

CCO[Si](CC)(CCCOCC1CO1)CCCOCC1CO1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 2/20 0.53
ALDH1A1 P00352 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614626 0.97 SMN1; SMN2 (0.56) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL613047 0.93 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL1997261 0.87 SMN1; SMN2 (0.50) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL15610112 0.86 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL614616 0.85 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL611564 0.85 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL17530160 0.84 SMN1; SMN2 (0.53) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL124764 0.84 SMN1; SMN2 (0.56) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL153462 0.83 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL511319 0.83 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-8299179-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120041136-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed