SCHEMBL6123917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6123763	0.89	CYP1A2 (0.62)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL13852255	0.82	CYP1A2 (0.43)	CYP1A2KMT2AGAAALDH1A1CYP2C19
	SCHEMBL10050900	0.81	CYP1A2 (0.42)	CYP1A2KMT2AMEN1ALDH1A1CYP2C19
	SCHEMBL13852028	0.77	CYP1A2 (0.67)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL13995003	0.77	CYP1A2 (0.66)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL13994998	0.76	CYP1A2 (1.00)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL10074812	0.76	CYP1A2 (0.46)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL6125337	0.76	CYP1A2 (0.46)	CYP1A2KMT2AMEN1GAAESR1
	SCHEMBL14402856	0.76	HSD17B10 (0.40)	CYP1A2KMT2AMEN1GAAALDH1A1
	SCHEMBL15442143	0.75	CYP1A2 (0.56)	CYP1A2KMT2AMEN1GAAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.