⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6127946 | 0.80 | — | — | |
| SCHEMBL927779 | 0.73 | — | — | |
| SCHEMBL291596 | 0.69 | — | — | |
| SCHEMBL14690462 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL22615270 | 0.67 | — | — | |
| SCHEMBL6127942 | 0.65 | — | — | |
| SCHEMBL14690898 | 0.65 | — | — | |
| SCHEMBL842096 | 0.65 | — | — | |
| SCHEMBL944236 | 0.65 | — | — | |
| SCHEMBL3043105 | 0.62 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026721-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| US-20120107328-A1 | GAMMA SECRETASE MODULATORS | MERCK SHARP & DOHME CORP. | 2012-05-03 | — | — | US | disclosed |