Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698260 | 0.86 | NAMPT (0.76) | NAMPT | |
| SCHEMBL3704764 | 0.83 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3704115 | 0.74 | NAMPT (0.78) | NAMPT | |
| SCHEMBL6128227 | 0.73 | NAMPT (0.74) | NAMPT | |
| SCHEMBL3713717 | 0.72 | NAMPT (0.69) | NAMPT | |
| SCHEMBL3710738 | 0.72 | NAMPT (0.74) | NAMPT | |
| SCHEMBL3700277 | 0.72 | NAMPT (0.71) | NAMPT | |
| SCHEMBL3706875 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3702025 | 0.71 | NAMPT (0.74) | NAMPT | |
| SCHEMBL3706205 | 0.71 | NAMPT (0.71) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640698-A1 | NAMPT AND ROCK INHIBITORS | AbbVie Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067965-A1 | NAMPT AND ROCK INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | disclosed |