SCHEMBL6128334

SCHEMBL6128334

CCN1CCS/C1=C\C=C\C1=[N+](C)c2ccccc2C1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FURIN P09958 1/20 0.47
MAPT P10636 8/20 0.47
APP P05067 3/20 0.47
MEN1 O00255 7/20 0.46
HTT P42858 7/20 0.46
KMT2A Q03164 7/20 0.46
LMNA P02545 6/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
NR2F2 P24468 1/20 0.46
RUNX1 Q01196 1/20 0.46
CBFB Q13951 1/20 0.46
THRB P10828 4/20 0.43
RECQL P46063 3/20 0.43
POLB P06746 3/20 0.43
PKM P14618 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066261 0.89 MAPT (0.55) FURINMAPTAPPMEN1HTT
SCHEMBL10066260 0.87 MAPT (0.46) FURINMAPTAPPMEN1HTT
SCHEMBL10066251 0.85 MAPT (0.49) FURINMAPTAPPMEN1HTT
SCHEMBL16314540 0.84 MAPT (0.46) FURINMAPTAPPMEN1HTT
SCHEMBL16299001 0.83 MAPT (0.42) FURINMAPTAPPMEN1HTT
SCHEMBL10066268 0.83 MAPT (0.43) FURINMAPTAPPMEN1HTT
SCHEMBL6128395 0.78 MEN1 (0.53) MAPTAPPMEN1HTTKMT2A
SCHEMBL10052790 0.77 MAPT (0.43) FURINMAPTAPPMEN1HTT
SCHEMBL10052792 0.75 MAPT (0.40) FURINMAPTAPPMEN1HTT
SCHEMBL14116791 0.74 MAPT (0.40) MAPTAPPMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760060-B2 Photopolymer formulations for producing holographic media having highly crosslinked matrix polymers COVESTRO DEUTSCHLAND AG (DE) 2017-09-12 US disclosed
US-9239408-B2 Colored photosensitive composition ADEKA CORPORATION (JP) 2016-01-19 US disclosed
US-9146456-B2 Photopolymer formulation for producing holographic media having highly crosslinked matrix polymers BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-09-29 US disclosed
US-20130306920-A1 COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-11-21 US disclosed
US-20130224634-A1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA HAVING HIGHLY CROSSLINKED MATRIX POLYMERS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-29 US disclosed
EP-2450893-A1 Photopolymer formula for producing of holographic media with highly networked matrix polymers Bayer MaterialScience AG (DE) 2012-05-09 EP disclosed