Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128586 | 1.00 | MAPT (0.50) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL36140 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL36375 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL36139 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL6885967 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPTDP1 | |
| Acetone SCHEMBL11807103 | 0.79 | MAPT (0.62) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL21126304 | 0.79 | ATM (0.46) | MAPTTDP1TSHRKMT2AALDH1A1 | |
| Acetone SCHEMBL11807108 | 0.79 | MAPT (0.62) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL9615428 | 0.78 | MAPT (0.49) | MAPTCACNA1BAPBA1APPTDP1 | |
| SCHEMBL7809914 | 0.78 | MAPT (0.67) | MAPTCACNA1BAPBA1APPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194336-A | — | — | None | — | — | JP | disclosed |
| JP-4134055-A | — | — | None | — | — | JP | disclosed |
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2012-05-24 | — | — | US | disclosed |
| JP-H05194336-A | AMINOACRYLIC ACID DERIVATIVE | KYORIN PHARMACEUT CO LTD | 1993-08-03 | — | — | JP | disclosed |
| JP-H04134055-A | DIALKYLAMINOACRYLIC ACID ALLYL ESTER AND PRODUCTION THEREOF | UBE IND LTD | 1992-05-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | PCNA, ERCC4, UBQLN2 | MAPT 2884/4885CACNA1B 3939/4885APBA1 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.