⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332168 | 0.88 | FFAR3 (0.33) | — | |
| SCHEMBL9032311 | 0.88 | CYP2C19 (0.36) | — | |
| SCHEMBL1964899 | 0.87 | — | — | |
| SCHEMBL27966019 | 0.87 | FFAR3 (0.40) | — | |
| SCHEMBL579748 | 0.86 | CYP2C19 (0.39) | — | |
| SCHEMBL28061196 | 0.86 | CYP2C19 (0.39) | — | |
| Hydrochloric Acid SCHEMBL28070089 | 0.84 | CYP2C19 (0.38) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL28874932 | 0.83 | GRM2 (0.44) | — | |
| SCHEMBL196273 | 0.83 | — | — | |
| SCHEMBL28108078 | 0.82 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | claimed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | claimed |
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | claimed |
| EP-1511718-B1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-05-06 | — | — | EP | claimed |
| US-7476760-B2 | Crystallization with a solvent mixture comprising a carboxylic acid and a poor solvent for 1-aminocyclopropanecarboxylic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-13 | — | — | US | claimed |
| CN-101213175-A | Bicyclic derivatives as p38 kinase inhibitors | PALAU PHARMA SA (ES) | 2008-07-02 | — | — | CN | claimed |
| EP-1907359-A2 | 3,5-SUBSTITUTED PIPERIDINE DERIVATIVES EFFECTIVE ON RENIN-RELATED DISORDERS | Novartis AG (CH) | 2008-04-09 | — | — | EP | claimed |
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | claimed |
| WO-2007006534-A2 | PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | claimed |
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | claimed |
| EP-1511718-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-09 | — | — | EP | claimed |
| CN-1558898-A | Antiviral agent | ��Ұ����ҩ��ʽ���� | 2004-12-29 | — | — | CN | claimed |
| US-6762320-B2 | MONOAMINE OXIDASE B INHIBITORS; ALZHEIMER'S DISEASE, SENILE DEMENTIA | HOFFMAN-LA ROCHE INC. | 2004-07-13 | — | — | US | claimed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | claimed |
| US-20030232883-A1 | N-acylamino benzyl ether derivatives | HOFFMANN-LA ROCHE INC. | 2003-12-18 | — | — | US | claimed |
| WO-2003099763-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-04 | — | — | WO | claimed |
| US-5739399-A | Process for the preparation of cyclopropanecarboxylic acid amides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | claimed |
| EP-0676390-B1 | Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride | HUELS CHEMISCHE WERKE AG (DE) | 1997-01-02 | — | — | EP | claimed |
| US-5569781-A | Process for the preparation of 1-aminocyclopropanecarboxylic acid hydrochloride | HUELS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | claimed |
| EP-0676390-A1 | Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride | HÜLS AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | claimed |