SCHEMBL6130058

SCHEMBL6130058

CCCCCCCCCCCCCCCCCC[n+]1ccccc1.O=S(=O)([O-])c1ccccc1

nearest known ligand 0.61

Known targets — ChEMBL curated mechanism

CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.61
ADRA2A P08913 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
CHRM1 P11229 2/20 0.61
ACHE P22303 2/20 0.61
SLC6A2 P23975 2/20 0.61
SLC6A4 P31645 2/20 0.61
SLC6A3 Q01959 2/20 0.61
ABCB11 O95342 1/20 0.61
ESR1 P03372 1/20 0.61
PGR P06401 1/20 0.61
HTR1A P08908 1/20 0.61
DRD1 P21728 1/20 0.61
TBXA2R P21731 1/20 0.61
PTGS1 P23219 1/20 0.61
PDE4A P27815 1/20 0.61
ADRA1A P35348 1/20 0.61
OPRM1 P35372 1/20 0.61
DRD3 P35462 1/20 0.61
KCNH2 Q12809 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936580 0.94 CHRM2 (0.50) CHRM2ADRA2AADORA3CHRM1ACHE
Cetylpyridinium SCHEMBL6217025 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL6517157 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL11141497 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL8939409 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL6929577 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL28329947 0.91 HTT (0.58) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL8397830 0.91 HTT (0.63) CHRM2ADRA2AADORA3CHRM1ACHE
Cetylpyridinium SCHEMBL2641632 0.86 RAD52 (0.53) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL10953084 0.86 HTT (0.50) CHRM2ADRA2AADORA3CHRM1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299402-A4 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES CHEVRON PHILLIPS CHEMICAL CO (US) 2005-09-28 EP disclosed
EP-1299402-A1 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES Philips Petroleum Company (US) 2003-04-09 EP disclosed
EP-1149071-A4 PROCESS FOR PRODUCING ORGANIC POLYSULFIDES PHILLIPS PETROLEUM CO (US) 2003-03-19 EP disclosed
US-6441229-B1 REACTING A SULFUR COMPOUND AND HALOGEN COMPOUND IN PRESENCE OF PHASE TRANSFER COMPOUND PHILLIPS PETROLEUM COMPANY 2002-08-27 US disclosed
EP-1080071-A4 A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND PHILLIPS PETROLEUM CO (US) 2002-06-26 EP disclosed
WO-2002000671-A1 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES PHILIPS PETROLEUM COMPANY (US) 2002-01-03 WO disclosed
EP-1149071-A1 PROCESS FOR PRODUCING ORGANIC POLYSULFIDES Phillips Petroleum Company (US) 2001-10-31 EP disclosed
EP-1080071-A1 A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND Phillips Petroleum Company (US) 2001-03-07 EP disclosed
US-6187960-B1 Process for producing organic polysulfide compounds PHILLIPS PETROLEUM COMPANY 2001-02-13 US disclosed
WO-2000043359-A1 PROCESS FOR PRODUCING ORGANIC POLYSULFIDES PHILLIPS PETROLEUM COMPANY (US) 2000-07-27 WO disclosed
US-4448892-A PALLADIUM COMPOUND, ETEROPOLYACID OR COPPER COMPONENT, SURFACTANT PHILLIPS PETROLEUM COMPANY (US) 1984-05-15 US disclosed
US-4434082-A FOR OXIDATION OF OLEFINS TO KETONES USING TWO PHASE DILUENT SYSTEM PHILLIPS PETROLEUM COMPANY (US) 1984-02-28 US disclosed
US-4419525-A OXIDATION OF OLEFINS TO KETONES, PALLADIUM, HETEROPOLYACID, SURFACTANT PHILLIPS PETROLEUM COMPANY (US) 1983-12-06 US disclosed
US-4299998-A Preparation of ethers PHILLIPS PETROLEUM CO. (US) 1981-11-10 US disclosed
US-4237071-A TO KETONES; ADDING A SURFACTANT TO THE SYSTEM TO IMPROVE CONVERSION AND SELECTIVITY PHILLIPS PETROLEUM COMPANY (US) 1980-12-02 US disclosed
US-4237331-A SEPARATING ISOBUTYLENES FROM AN OLEFIN STREAM BY FORMING CARBONYL COMPOUNDS IN THE PRESENCE OF A CATALYST COMPRISING A PALLADIUM COMPONENT, A COPPER COMPONENT AND A BORIC ACID PHILLIPS PETROLEUM COMPANY (US) 1980-12-02 US disclosed
US-4220604-A CONVERSION OF ISOOLEFIN TO KETONE PHILLIPS PETROLEUM COMPANY (US) 1980-09-02 US disclosed
US-4203927-A A TWO-PHASE AQUEOUS DILUENT, A CATALYST OF PALLADIUM, COPPER AND BORON COMPOUNDS, AND A SURFACTANT TO PRODUCE A CARBONYL COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1980-05-20 US disclosed
US-4152354-A OLEFIN OXIDATION PROCESS PHILLIPS PETROLEUM COMPANY (US) 1979-05-01 US disclosed
EP-0000143-A1 Olefin oxidation process PHILLIPS PETROLEUM COMPANY (US) 1979-01-10 EP disclosed