Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364134 | 0.83 | MAPT (0.53) | HSD17B10PTPN1MEN1KMT2ANPC1 | |
| SCHEMBL5364129 | 0.83 | MAPT (0.53) | HSD17B10PTPN1MEN1KMT2ANPC1 | |
| SCHEMBL5368826 | 0.76 | HSD17B10 (0.53) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5368828 | 0.76 | HSD17B10 (0.53) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5362944 | 0.70 | PTPN1 (0.56) | PTPN1MEN1KMT2ANPC1MAPT | |
| SCHEMBL5362936 | 0.70 | PTPN1 (0.56) | PTPN1MEN1KMT2ANPC1MAPT | |
| SCHEMBL5364167 | 0.68 | MAPT (0.71) | PTPN1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5364159 | 0.68 | MAPT (0.71) | PTPN1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5362621 | 0.68 | MAPT (0.61) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL5362626 | 0.68 | MAPT (0.61) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349613-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2005-09-21 | — | — | EP | claimed |
| EP-1349613-A2 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2003-10-08 | — | — | EP | claimed |
| WO-2002049413-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |