Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.57 |
| ▸ | HTR2B | P41595 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130290 | 1.00 | HTR2C (0.57) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL1600657 | 0.85 | HTR2C (0.58) | HTR2CHTR2BHTR2AMAOBKDM1A | |
| SCHEMBL13305511 | 0.85 | HTR2C (0.58) | HTR2CHTR2BHTR2AMAOBKDM1A | |
| SCHEMBL4587814 | 0.85 | HTR2C (0.53) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL6560502 | 0.81 | HTR2C (0.53) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL6560516 | 0.81 | HTR2C (0.53) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL24663868 | 0.80 | HTR2C (0.53) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL20009113 | 0.80 | HTR2C (0.53) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL6228607 | 0.78 | HTR2C (0.50) | HTR2CHTR2BHTR2AMAOBCNR1 | |
| SCHEMBL6228608 | 0.78 | HTR2C (0.50) | HTR2CHTR2BHTR2AMAOBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347952-A4 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1026151-B1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1347952-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002046142-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2002-06-13 | — | — | WO | disclosed |
| EP-1026151-A1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |
| US-6063956-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED | ROHM AND HAAS COMPANY (US) | 2000-05-16 | — | — | US | disclosed |