Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880239 | 0.88 | — | — | |
| SCHEMBL16978088 | 0.88 | — | — | |
| SCHEMBL17322737 | 0.84 | HTT (0.50) | CYP3A4TSHRMEN1THRBHTT | |
| SCHEMBL10331167 | 0.82 | TSHR (0.38) | CYP3A4TSHRMEN1THRBHTT | |
| SCHEMBL19319600 | 0.80 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL19319599 | 0.80 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL19319604 | 0.80 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL15164054 | 0.79 | MEN1 (0.41) | CYP3A4TSHRMEN1THRBHTT | |
| SCHEMBL19728324 | 0.79 | TSHR (0.36) | CYP3A4TSHRMEN1THRBHTT | |
| SCHEMBL16942557 | 0.79 | CYP3A4 (0.33) | CYP3A4TSHRMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453602-A4 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECH INC (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-1453602-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2002092766-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2002-11-21 | — | — | WO | disclosed |