SCHEMBL6130709

SCHEMBL6130709

N=CCNCCCC[C@H](N)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
GSR P00390 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DDAH1 O94760 2/20 0.32
LTA4H P09960 2/20 0.31
SLC15A1 P46059 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
NOS3 P29474 2/20 0.30
NOS1 P29475 2/20 0.30
NOS2 P35228 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
ARG1 P05089 3/20 0.30
ARG2 P78540 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL934762 0.86 GSR (0.48) GSRDDAH1NOS3NOS1NOS2
SCHEMBL7974900 0.86 GSR (0.48) GSRDDAH1NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL7974008 0.85 GSR (0.47) GSRDDAH1NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL4424849 0.85 GSR (0.47) GSRDDAH1NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL4581849 0.85 GSR (0.47) GSRDDAH1NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL7977023 0.85 GSR (0.47) GSRDDAH1NOS3NOS1NOS2
SCHEMBL7974904 0.82 DPP7 (0.35) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL4316097 0.81 GSR (0.46) GSRDDAH1NOS3NOS1NOS2
SCHEMBL21067514 0.81 GSR (0.46) GSRDDAH1NOS3NOS1NOS2
SCHEMBL1504429 0.81 GSR (0.46) GSRDDAH1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463495-A4 AGENTS AND METHODS FOR TREATMENT OF CANCER PHARMACIA CORP (US) 2005-11-16 EP disclosed
EP-1463495-A2 AGENTS AND METHODS FOR TREATMENT OF CANCER Pharmacia Corporation (US) 2004-10-06 EP disclosed
WO-2002076395-A2 AGENTS AND METHODS FOR TREATMENT OF CANCER PHARMACIA CORPORATION (US) 2002-10-03 WO disclosed