Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25438602 | 1.00 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27668417 | 0.92 | ESR1 (0.41) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30931415 | 0.88 | ESR1 (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27485575 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27660493 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28872440 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27660486 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL994804 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29849835 | 0.88 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL205695 | 0.84 | KAT8 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115734984-A | Polypropylene resin composition | 住友化学株式会社 | 2023-03-03 | — | — | CN | disclosed |
| US-6945000-B1 | Metal foil masonry flashings and termination bar therefor | HOHMANN & BARNARD, INC. (US) | 2005-09-20 | — | — | US | disclosed |
| US-5610239-A | RUBBER, GLYOXAL | REICHHOLD CHEMICALS, INC. (US) | 1997-03-11 | — | — | US | disclosed |
| US-5441999-A | Hot melt adhesive | REICHHOLD CHEMICALS, INC. (US) | 1995-08-15 | — | — | US | disclosed |