Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894434 | 0.77 | KDM4E (0.48) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL301403 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL11689296 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL3376067 | 0.77 | KDM4E (0.48) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL9166773 | 0.77 | KDM4E (0.48) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL14822849 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL190395 | 0.77 | KDM4E (0.48) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL10713806 | 0.76 | KDM4E (0.47) | KDM4ELMNAALDH1A1GAATDP1 | |
| SCHEMBL10713804 | 0.76 | KDM4E (0.47) | KDM4ELMNAALDH1A1GAATDP1 | |
| Water SCHEMBL7734213 | 0.76 | KDM4E (0.57) | KDM4ELMNAALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551913-A2 | SILICA-RUBBER MIXTURES HAVING IMPROVED HARDNESS | GENERAL ELECTRIC COMPANY (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004005395-A2 | SILICA-RUBBER MIXTURES HAVING IMPROVED HARDNESS | GENERAL ELECTRIC COMPANY (US) | 2004-01-15 | — | — | WO | disclosed |