Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6131870 | 0.99 | OGA (0.58) | OGAALDH1A1CDK5CDK5R1KDM4E | |
| Water SCHEMBL7685626 | 0.99 | OGA (0.58) | OGAALDH1A1CDK5CDK5R1KDM4E | |
| SCHEMBL6131879 | 0.84 | OGA (0.59) | OGAALDH1A1CDK5CDK5R1KDM4E | |
| SCHEMBL6131981 | 0.84 | OGA (0.61) | OGAKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL6131897 | 0.83 | OGA (0.58) | OGAALDH1A1CDK5CDK5R1KDM4E | |
| Hydrochloric Acid SCHEMBL7690290 | 0.82 | OGA (0.59) | OGAKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL7690292 | 0.82 | OGA (0.59) | OGAKDM4ENPSR1 | |
| SCHEMBL6131973 | 0.81 | HRH3 (0.56) | OGAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL6131939 | 0.81 | GAA (0.55) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7688425 | 0.81 | OGA (0.51) | OGAALDH1A1CDK5CDK5R1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |