Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132255 | 1.00 | MAPT (0.51) | MAPTRAB9AAKR1C3KMT2ATSHR | |
| SCHEMBL18436831 | 0.77 | MAPT (0.57) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL327800 | 0.77 | MAPT (0.57) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL7790503 | 0.77 | MAPT (0.57) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL24352865 | 0.77 | MAPT (0.57) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL23731989 | 0.77 | MAPT (0.57) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL20456767 | 0.76 | KMT2A (0.48) | MAPTRAB9AKMT2AALDH1A1PIK3CA | |
| SCHEMBL20217175 | 0.76 | MAPT (0.56) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL13370273 | 0.76 | MAPT (0.56) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL13144984 | 0.76 | MAPT (0.56) | MAPTRAB9AKMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |