Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ME2 | P23368 | 4/20 | 0.66 |
| ▸ | ME1 | P48163 | 4/20 | 0.66 |
| ▸ | ME3 | Q16798 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727540 | 0.93 | NPSR1 (0.68) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL19950156 | 0.89 | MEN1 (0.60) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL894510 | 0.89 | MEN1 (0.60) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL975238 | 0.89 | NPSR1 (0.60) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL12814257 | 0.89 | MEN1 (0.60) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL6132579 | 0.88 | MEN1 (0.59) | GAAMAPTKDM4ELMNAME2 | |
| Hydrochloric Acid SCHEMBL3934434 | 0.88 | MEN1 (0.59) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL8642538 | 0.88 | MEN1 (0.59) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL11889651 | 0.87 | MAPT (0.65) | GAAMAPTKDM4ELMNAME2 | |
| SCHEMBL23201166 | 0.87 | CA1 (0.58) | GAAMAPTKDM4ELMNAME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |