Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135026 | 0.86 | MKNK1 (0.47) | MKNK1MKNK2PDE4DPDE7AUSP2 | |
| SCHEMBL6134578 | 0.84 | MKNK1 (0.46) | MKNK1MKNK2USP2ITGA2BPIM1 | |
| SCHEMBL6134521 | 0.84 | MKNK1 (0.45) | MKNK1MKNK2ITGA2BPIM1 | |
| SCHEMBL6134954 | 0.84 | MKNK1 (0.47) | MKNK1MKNK2USP2ALDH1A1MAPT | |
| SCHEMBL6133900 | 0.83 | MKNK1 (0.45) | MKNK1MKNK2USP2PIM1FYN | |
| SCHEMBL6132394 | 0.82 | MKNK1 (0.46) | MKNK1MKNK2USP2ITGA2BPIM1 | |
| SCHEMBL6132440 | 0.82 | MKNK1 (0.41) | MKNK1MKNK2USP2ALDH1A1TP53 | |
| SCHEMBL6132170 | 0.82 | MKNK1 (0.45) | MKNK1MKNK2USP2ITGA2BPIM1 | |
| SCHEMBL6132626 | 0.80 | TP53 (0.46) | PDE4DPDE7AUSP2ITGA2BTP53 | |
| SCHEMBL6134934 | 0.80 | MKNK1 (0.47) | MKNK1MKNK2PDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |