Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132851 | 0.98 | MAPT (0.42) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132778 | 0.91 | MAPT (0.42) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132920 | 0.89 | MAPT (0.42) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132995 | 0.84 | HDAC3 (0.39) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132659 | 0.84 | MAPT (0.38) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132446 | 0.83 | HDAC3 (0.39) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132854 | 0.83 | MAPT (0.39) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6134866 | 0.81 | MAPT (0.44) | MAPTTP53LMNACA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6132409 | 0.80 | MAPT (0.41) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6135143 | 0.80 | MAPT (0.42) | MAPTTP53LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |