Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132348 | 0.99 | HPGD (0.46) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL6132665 | 0.97 | HPGD (0.47) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL792038 | 0.91 | HPGD (0.49) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL13096783 | 0.89 | HPGD (0.47) | HPGDRECQLEPHX1GPR119PRMT5 | |
| SCHEMBL5039027 | 0.87 | HPGD (0.46) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL27380171 | 0.87 | HPGD (0.46) | HPGDRECQLEPHX1GPR119PRMT5 | |
| SCHEMBL15362664 | 0.87 | HPGD (0.46) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL5268640 | 0.87 | PDE4D (0.49) | HPGDRECQLEPHX1GPR119PDE4A | |
| SCHEMBL25960265 | 0.87 | HPGD (0.48) | HPGDRECQLEPHX1GPR119KDM4E | |
| SCHEMBL4219721 | 0.87 | HPGD (0.48) | HPGDRECQLEPHX1GPR119PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |