Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132263 | 0.99 | CHRNA10 (0.43) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6134054 | 0.88 | HRH3 (0.50) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6135614 | 0.85 | CHRNA10 (0.50) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6134368 | 0.84 | CHRNA10 (0.44) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6135256 | 0.83 | CHRNA10 (0.43) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6134370 | 0.82 | CHRNA10 (0.52) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL20346944 | 0.80 | KDM4E (0.53) | CHRNA10CHRNA9KDM4ETP53HRH3 | |
| SCHEMBL6135382 | 0.77 | HRH3 (0.57) | KDM4ETP53HRH3HRH1 | |
| SCHEMBL6135083 | 0.77 | HRH3 (0.57) | KDM4ETP53HRH3HRH1 | |
| SCHEMBL6135057 | 0.77 | HRH3 (0.57) | KDM4ETP53HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |