Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cetrorelix. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR known ✓ | P30968 | 12/20 | 0.89 |
| ▸ | DRD1 | P21728 | 1/20 | 0.89 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.89 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.89 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetrorelix SCHEMBL30883014 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL30742606 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL29887354 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL24040297 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL30882994 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL24040283 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL571416 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL24040296 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL30882997 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 | |
| Cetrorelix SCHEMBL27794687 | 1.00 | GNRHR (0.89) | GNRHRDRD1OPRM1MRGPRX2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18031 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599384-B | Stable parenteral dosage form of cetrorelix acetate | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2026-05-26 | — | — | CN | claimed |
| CN-122070930-A | Preparation composition of Qu Rui g of injection acetic acid and preparation method thereof | 浙江和泽医药科技股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-20260124148-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | BHAMIS RES LABORATORY PVT LTD (IN) | 2026-05-07 | — | — | US | claimed |
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| US-20260096905-A1 | IMPLANTABLE DRUG-DEVICE COMBINATIONS, AND RELATED METHODS OF TREATMENT | PITUVIA THERAPEUTICS INC (US) | 2026-04-09 | — | — | US | claimed |
| EP-4525938-B1 | RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS | BAYER AG (DE) | 2026-03-11 | — | — | EP | claimed |
| US-20260034192-A1 | USE OF GNRH ANTAGONISTS IN MAMMALS TO SYNCHRONIZE FOLLICULAR WAVE EMERGENCE | UNIV SASKATCHEWAN (CA) | 2026-02-05 | — | — | US | claimed |
| US-12533321-B2 | Polypeptide formulations for oral delivery | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2026-01-27 | — | — | US | claimed |
| US-12522572-B2 | Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-01-13 | — | — | US | claimed |
| WO-1997027863-A1 | COMBINED PHARMACEUTICAL PREPARATION CONTAINING LHRH-ANALOGOUS SUBSTANCES AND ANTI-ESTROGENS FOR TREATING GYNAECOLOGICAL DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | claimed |
| US-5635161-A | PULMONARY DELIVERY | ABBOTT LABORATORIES (US) | 1997-06-03 | — | — | US | claimed |
| EP-0771189-A1 | INHALATION COMPOSITION | ARZNEIMITTELWERK DRESDEN GmbH, FACHBEREICH PATENTE (DE) | 1997-05-07 | — | — | EP | claimed |
| WO-1996040089-A2 | AEROSOL DRUG FORMULATIONS CONTAINING VEGETABLE OILS | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0732934-A1 | LONG-ACTING INJECTION SUSPENSIONS AND A PROCESS FOR THEIR PREPARATION | ASTA Medica Aktiengesellschaft (DE) | 1996-09-25 | — | — | EP | claimed |
| WO-1996002231-A1 | INHALATION COMPOSITION | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | claimed |
| CN-1112019-A | Novel process for the preparation of cetrorelix lyophilisate | ASTA MEDICA AG (DE) | 1995-11-22 | — | — | CN | claimed |
| WO-1995015767-A1 | LONG-ACTING INJECTION SUSPENSIONS AND A PROCESS FOR THEIR PREPARATION | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1995-06-15 | — | — | WO | claimed |
| EP-0657170-A1 | Products for the application of high initial doses of cetrorelix and preparation of a combined package for use in treating diseases | ASTA Medica Aktiengesellschaft (DE) | 1995-06-14 | — | — | EP | claimed |
| EP-0611572-A2 | Process to prepare a cetrorelix lyophilised composition | ASTA Medica Aktiengesellschaft (DE) | 1994-08-24 | — | — | EP | claimed |