Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 6/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 6/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41008 | 0.91 | LRRK2 (0.44) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL613379 | 0.89 | LRRK2 (0.47) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL41398 | 0.87 | LRRK2 (0.41) | LRRK2JAK2SRCPDGFRBTTK | |
| SCHEMBL41596 | 0.85 | LRRK2 (0.43) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL41009 | 0.84 | LRRK2 (0.47) | LRRK2JAK2SRCPDGFRBTTK | |
| SCHEMBL41063 | 0.84 | JAK2 (0.44) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL41122 | 0.83 | SRC (0.53) | LRRK2JAK2SRCPDGFRBTTK | |
| SCHEMBL612670 | 0.82 | SRC (0.45) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL42778 | 0.82 | LRRK2 (0.41) | LRRK2JAK2SRCABL1PDGFRB | |
| SCHEMBL41292 | 0.81 | LRRK2 (0.49) | LRRK2JAK2SRCABL1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041195-A1 | Heterocyclic compounds | FOVEA PHARMACEUTICALS | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041195-A1 | Heterocyclic compounds | MAP3K1, MAP3K5, MAP3K2 | LRRK2 391/4885JAK2 325/4885SRC 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.