Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299033 | 0.92 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2PTPN1 | |
| SCHEMBL6299265 | 0.91 | PPARG (0.58) | PPARGALDH1A1MAPTSMN1; SMN2PTPN1 | |
| SCHEMBL6489866 | 0.89 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6299715 | 0.88 | PPARG (0.73) | PPARGALDH1A1MAPTSMN1; SMN2HDAC3 | |
| SCHEMBL6299907 | 0.87 | PPARG (0.54) | PPARGALDH1A1MAPTSMN1; SMN2PTPN1 | |
| SCHEMBL6306107 | 0.87 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6299466 | 0.86 | PPARG (0.59) | PPARGALDH1A1MAPTSMN1; SMN2PTPN1 | |
| SCHEMBL6504715 | 0.86 | PPARG (0.60) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6492946 | 0.86 | PPARG (0.57) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6299056 | 0.86 | PPARG (0.69) | PPARGALDH1A1MAPTSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197376-A1 | Concomitant drugs | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-09-08 | — | — | US | claimed |
| US-20050197376-A1 | Concomitant drugs | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-09-08 | — | — | US | disclosed |