SCHEMBL6134470

SCHEMBL6134470

CCCCCS(=O)(=O)NC(=O)C=Cc1c(Br)nc(C)n1Cc1ccc(Cl)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.61
PTGER3 P43115 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6134465 1.00 PPARG (0.61) PPARGPTGER3
SCHEMBL6183218 0.91 PPARG (0.63) PPARGPTGER3
SCHEMBL6183211 0.91 PPARG (0.63) PPARGPTGER3
SCHEMBL6180254 0.87 PPARG (0.58) PPARGPTGER3
SCHEMBL6180259 0.87 PPARG (0.58) PPARGPTGER3
SCHEMBL3202438 0.84 PPARG (0.62) PPARGPTGER3
SCHEMBL3202431 0.84 PPARG (0.62) PPARGPTGER3
SCHEMBL6181012 0.83 PPARG (0.68) PPARG
SCHEMBL6181016 0.83 PPARG (0.68) PPARG
SCHEMBL6181991 0.82 PPARG (0.64) PPARGPTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000932-B9 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2005-12-28 EP disclosed
US-20050197376-A1 Concomitant drugs FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-09-08 US disclosed
EP-1000932-B1 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2004-09-15 EP disclosed
US-6242474-B1 SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-05 US disclosed
EP-1000932-A1 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-05-17 EP disclosed