Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135137 | 0.91 | HRH3 (0.45) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6135117 | 0.90 | HRH3 (0.42) | HRH3MEN1KMT2AUSP2WNT3A | |
| SCHEMBL6134820 | 0.82 | HRH3 (0.47) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6134683 | 0.82 | HDAC3 (0.41) | HRH3MEN1KMT2AWNT3A | |
| SCHEMBL6135547 | 0.82 | HRH3 (0.52) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6134229 | 0.81 | HRH3 (0.44) | HRH3MEN1KMT2AUSP2WNT3A | |
| SCHEMBL6135370 | 0.81 | USP2 (0.55) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6135376 | 0.81 | USP2 (0.55) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6134222 | 0.81 | HRH3 (0.53) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL6134406 | 0.81 | HRH3 (0.53) | HRH3MEN1KMT2ACSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | HRH3 1440/4885MEN1 880/4885KMT2A 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.