Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134510 | 1.00 | PPARG (0.74) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL6134981 | 0.92 | PPARG (0.62) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL6134985 | 0.92 | PPARG (0.62) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL7659181 | 0.89 | PPARG (0.59) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL7659185 | 0.89 | PPARG (0.59) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL6304167 | 0.88 | PPARG (0.65) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL7652185 | 0.87 | PPARG (0.58) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL7652190 | 0.87 | PPARG (0.58) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL6134141 | 0.87 | PPARG (0.68) | PPARGHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL6134137 | 0.87 | PPARG (0.68) | PPARGHDAC1HDAC6HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197376-A1 | Concomitant drugs | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-09-08 | — | — | US | disclosed |