Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 12/20 | 0.80 |
| ▸ | AMY1A | P0DUB6 | 12/20 | 0.80 |
| ▸ | GAA | P10253 | 12/20 | 0.80 |
| ▸ | SI | P14410 | 12/20 | 0.80 |
| ▸ | MGAM2 | Q2M2H8 | 12/20 | 0.80 |
| ▸ | F12 | P00748 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482235 | 0.97 | MGAM (0.76) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27466934 | 0.92 | MGAM (0.69) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27481488 | 0.91 | MGAM (0.67) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27468359 | 0.91 | MGAM (0.67) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27482232 | 0.90 | MGAM (0.66) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27481100 | 0.86 | MGAM (0.93) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8780395 | 0.84 | MGAM (0.73) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27482234 | 0.84 | MGAM (0.58) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8780356 | 0.83 | MGAM (0.78) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27482532 | 0.83 | MGAM (0.78) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1366066-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072621-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | MGAM 12/4885AMY1A 131/4885GAA 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.