Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135390 | 0.89 | PDE4D (0.45) | USP2HRH3PDE4DPDE7AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7314046 | 0.82 | CSNK2A2 (0.49) | USP2CSNK2A2CSNK2A1NR1H4HRH3 | |
| SCHEMBL6132526 | 0.82 | CSNK2A2 (0.45) | USP2CSNK2A2CSNK2A1NR1H4HRH3 | |
| SCHEMBL6135503 | 0.82 | CSNK2A2 (0.52) | USP2CSNK2A2CSNK2A1NR1H4HRH3 | |
| SCHEMBL6135371 | 0.81 | HDAC3 (0.43) | USP2HRH3ALDH1A1TP53MAPT | |
| SCHEMBL6235038 | 0.81 | CSNK2A2 (0.46) | USP2CSNK2A2CSNK2A1NR1H4PDE4D | |
| SCHEMBL6134390 | 0.81 | CSNK2A2 (0.53) | USP2CSNK2A2CSNK2A1NR1H4CSNK2B | |
| SCHEMBL6132376 | 0.80 | CSNK2A2 (0.46) | USP2CSNK2A2CSNK2A1NR1H4HRH3 | |
| SCHEMBL7340640 | 0.80 | CSNK2A2 (0.54) | USP2CSNK2A2CSNK2A1NR1H4HRH3 | |
| SCHEMBL6135608 | 0.79 | NR1H4 (0.48) | USP2CSNK2A2CSNK2A1NR1H4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1366066-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072621-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | USP2 4776/4885CSNK2A2 1527/4885CSNK2A1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.