Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313043 | 0.92 | TP53 (0.50) | TP53EPHX2CA12CA1CA2 | |
| SCHEMBL6134926 | 0.88 | HRH3 (0.46) | HRH3KCNH2TP53CA12CA1 | |
| Hydrochloric Acid SCHEMBL6132465 | 0.85 | TP53 (0.46) | HRH3TP53CA12CA1CA2 | |
| SCHEMBL6134517 | 0.85 | TP53 (0.50) | KCNH2TP53EPHX2CA12CA1 | |
| SCHEMBL6134689 | 0.84 | CA12 (0.40) | HRH3TP53CA12CA1CA2 | |
| SCHEMBL6135285 | 0.83 | EPHX2 (0.52) | HRH3KCNH2EPHX2ADRA1A | |
| SCHEMBL6134951 | 0.82 | CA12 (0.52) | TP53CA12CA1CA2CA9 | |
| SCHEMBL6133887 | 0.82 | HDAC3 (0.42) | HRH3KCNH2TP53CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6937886 | 0.82 | TP53 (0.42) | HRH3TP53CA12CA1CA2 | |
| SCHEMBL6134934 | 0.81 | MKNK1 (0.47) | HRH3KCNH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | HRH3 1440/4885KCNH2 2774/4885TP53 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.