Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194236 | 1.00 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL19210221 | 1.00 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| Zinc Ion SCHEMBL9731009 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL9679131 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL10731314 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| Zinc Ion SCHEMBL10726528 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| Zinc Ion SCHEMBL9704026 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL9679116 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL10732351 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD | |
| SCHEMBL11860350 | 0.96 | FABP3 (0.50) | FABP3CES2CES1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109248154-A | A kind of rosuvastatin calcium tablets and preparation method thereof | 瀚晖制药有限公司 | 2019-01-22 | — | — | CN | claimed |
| EP-2787987-B1 | NEW PHARMACEUTICAL STATIN COMPOSITIONS | HEXAL AG (DE) | 2016-06-01 | — | — | EP | claimed |
| CN-103169680-B | Diclofenac sodium sustained-release tablet and method for preparing same | SHENZHEN GUOYUAN PHARMACEUTICAL CO LTD | 2015-05-06 | — | — | CN | claimed |
| EP-2787987-A1 | NOVEL PHARMACEUTICAL STATIN COMPOSITION | Hexal AG (DE) | 2014-10-15 | — | — | EP | claimed |
| CN-103169680-A | Diclofenac sodium sustained-release tablet and method for preparing same | SHENZHEN GUOYUAN PHARMACEUTICAL CO LTD | 2013-06-26 | — | — | CN | claimed |
| WO-2013083674-A1 | NOVEL PHARMACEUTICAL STATIN COMPOSITION | HEXAL AG (DE) | 2013-06-13 | — | — | WO | claimed |
| CN-101732267-B | Pravastatin sodium tablet, application and preparation method thereof | LIVZON PHARMACEUTICAL GROUP | 2012-05-30 | — | — | CN | claimed |
| CN-101732267-A | Pravastatin sodium tablet as well as application and preparation method thereof | LIVZON PHARMACEUTICAL GROUP IN | 2010-06-16 | — | — | CN | claimed |
| EP-4313155-A1 | ORAL FORMULATION OF IVERMECTIN AND USES THEREOF | Substipharm (FR) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200402-A1 | ORAL FORMULATION OF IVERMECTIN AND USES THEREOF | SUBSTIPHARM (FR) | 2022-09-29 | — | — | WO | disclosed |
| EP-4062907-A1 | FORMULATION FOR ORAL ADMINISTRATION OF IVERMECTIN AND USES THEREOF | Substipharm (FR) | 2022-09-28 | — | — | EP | disclosed |
| CN-109248154-A | A kind of rosuvastatin calcium tablets and preparation method thereof | 瀚晖制药有限公司 | 2019-01-22 | — | — | CN | disclosed |
| EP-2787987-B1 | NEW PHARMACEUTICAL STATIN COMPOSITIONS | HEXAL AG (DE) | 2016-06-01 | — | — | EP | disclosed |
| CN-103169680-B | Diclofenac sodium sustained-release tablet and method for preparing same | SHENZHEN GUOYUAN PHARMACEUTICAL CO LTD | 2015-05-06 | — | — | CN | disclosed |
| EP-0315574-A2 | Renin inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-10 | — | — | EP | disclosed |
| EP-0310015-A2 | Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | disclosed |
| EP-0203450-A2 | Derivatives of bicyclic amino acids process for their preparation, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-03 | — | — | EP | disclosed |