⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291712 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5152591 | 0.97 | CHRM1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL246538 | 0.97 | CHRM1 (0.35) | — | |
| SCHEMBL9245079 | 0.87 | SLC1A3 (0.32) | — | |
| SCHEMBL18510157 | 0.83 | CHRM1 (0.36) | — | |
| SCHEMBL27955925 | 0.80 | CHRM1 (0.38) | — | |
| SCHEMBL18762848 | 0.80 | USP2 (0.35) | — | |
| SCHEMBL29956838 | 0.79 | — | — | |
| SCHEMBL1320264 | 0.79 | CHRM1 (0.56) | — | |
| SCHEMBL16586241 | 0.79 | CHRM1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539128-A2 | USE OF SKIN-PROTECTING SUBSTANCES | Phenion GmbH & Co KG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026295-A9 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO KG (DE) | 2004-09-16 | — | — | WO | claimed |
| WO-2004026295-A2 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO. KG (DE) | 2004-04-01 | — | — | WO | claimed |
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| US-11066416-B2 | Rapafucin derivative compounds and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210094933-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2021-04-01 | — | — | US | disclosed |
| US-20200040004-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RAPAFUSYN PHARMACEUTICALS, INC. | 2020-02-06 | — | — | US | disclosed |
| EP-1539128-A2 | USE OF SKIN-PROTECTING SUBSTANCES | Phenion GmbH & Co KG (DE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004026295-A9 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO KG (DE) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004026295-A2 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO. KG (DE) | 2004-04-01 | — | — | WO | disclosed |