⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinchlorimide SCHEMBL5897812 | 0.85 | — | — | |
| Succinchlorimide SCHEMBL1465495 | 0.85 | BRD4 (0.30) | — | |
| Succinchlorimide SCHEMBL72 | 0.85 | — | — | |
| SCHEMBL14686081 | 0.85 | BRD4 (0.30) | — | |
| SCHEMBL18779 | 0.85 | — | — | |
| SCHEMBL1058967 | 0.85 | — | — | |
| Succinchlorimide SCHEMBL613519 | 0.82 | — | — | |
| Succinchlorimide SCHEMBL3032531 | 0.82 | — | — | |
| Succinchlorimide SCHEMBL31009667 | 0.82 | — | — | |
| Succinchlorimide SCHEMBL30695169 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540826-B | Spiro-fused piperidine derivatives useful as inhibitors of extrarenal potassium channels | 默沙东公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107922394-A | 3 tetrazole radical benzene, 1,2 disulfonic acid amide derivative as metal beta lactamase restrainer | 默沙东公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107602583-A | A kind of synthetic method of jak kinase inhibitor intermediate | 中南林业科技大学 | 2018-01-19 | — | — | CN | disclosed |
| CN-106916091-A | Cathepsin K inhibitor and application thereof | 广东东阳光药业有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106660986-A | Inhibitors of renal outer medullary potassium channels | 默沙东公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106488912-A | Inhibitors of renal outer medullary potassium channels | 默沙东公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-104507928-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-1363516-B1 | AN IMPROVED PROCESS FOR PREPARING SIMVASTATIN | CHONG KUN DANG PHARM CORP (KR) | 2005-08-31 | — | — | EP | disclosed |
| US-6833461-B2 | Process for preparing simvastatin | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-12-21 | — | — | US | disclosed |
| US-20040068123-A1 | Process for preparing simvastatin | CHONG KUN DANG PHARMACUETICAL CORP. (KR) | 2004-04-08 | — | — | US | disclosed |