Naphthoic Acid

Naphthoic Acid

SCHEMBL6135820

C=C.C=C.O=C(O)c1cccc2ccccc12

nearest known ligand 0.91

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.91
NR4A2 P43354 1/20 0.91
NR4A3 Q92570 1/20 0.91
CDC25B P30305 2/20 0.71
WDR5 P61964 1/20 0.59
PTPN1 P18031 2/20 0.58
LDHA P00338 1/20 0.57
MMP3 P08254 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
PLK1 P53350 1/20 0.55
ALDH1A1 P00352 3/20 0.54
ALOX15 P16050 1/20 0.54
PTK2B Q14289 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GFER P55789 1/20 0.53
CNR2 P34972 2/20 0.51
KDM4E B2RXH2 2/20 0.51
HPGD P15428 2/20 0.50
HSD17B10 Q99714 1/20 0.50
CNR1 P21554 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoic Acid SCHEMBL6253403 1.00 NR4A1 (0.91) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL28070576 0.96 NR4A1 (0.91) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL28110155 0.96 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL29352220 0.96 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL17258 0.96 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL30233567 0.96 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL1407017 0.93 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL868316 0.93 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL9178942 0.93 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BWDR5
Naphthoic Acid SCHEMBL6912565 0.93 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BWDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201423-B1 LAYERED PLASTIC MOLDING YOSHINO KOGYOSHO CO LTD (JP) 2005-06-22 EP disclosed