SCHEMBL6136088

SCHEMBL6136088

N#CC1=CC=COC1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030453 0.74
Hydrochloric Acid SCHEMBL538105 0.68
SCHEMBL11316193 0.67
SCHEMBL12287529 0.67
SCHEMBL8968822 0.65
SCHEMBL30022 0.65
SCHEMBL19418026 0.61
SCHEMBL21987848 0.60
SCHEMBL18284222 0.60
SCHEMBL28548653 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303176-B Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2022-08-16 CN claimed
CN-111303176-A Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2020-06-19 CN claimed
CN-111303176-B Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2022-08-16 CN disclosed
CN-111303176-B Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2022-08-16 CN disclosed
CN-111303176-A Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2020-06-19 CN disclosed
CN-111303176-A Chrysin spliced 2-amino 3-cyanopyran compound and preparation method and application thereof 贵州大学 2020-06-19 CN disclosed
EP-0777492-B1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORP (US) 2005-01-19 EP disclosed
EP-0777492-A4 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORP (US) 2002-11-27 EP disclosed
US-5958792-A DERIVATIZING SOLID SUPPORT SURFACES WITH A GROUP CONSISTING OF O AND NH TO PROVIDE PLURALITY OF DERIVATIZED SUPPORT SURFACES, DIVIDING THEM INTO SUBAMOUNTS, REACTING DIFFERENT SUBMONOMER WITH ACTIVE GROUP OF SUBAMOUNT, RECOMBINING CHIRON CORPORATION (US) 1999-09-28 US disclosed
EP-0777663-B1 USE OF SUBSTITUTED 6-AMINO-4H-PYRANS BAYER AG (DE) 1999-05-26 EP disclosed
EP-0777492-A1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORPORATION (US) 1997-06-11 EP disclosed
WO-1996040201-A1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORPORATION (US) 1996-12-19 WO disclosed