Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 13/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135900 | 0.87 | ESR1 (0.62) | ESR1ESR2LTA4HSSTR2CHEK2 | |
| SCHEMBL6135934 | 0.84 | ESR1 (0.63) | ESR1ESR2LTA4HSSTR2CHEK2 | |
| SCHEMBL6136054 | 0.84 | ESR1 (0.63) | ESR1ESR2LTA4HSSTR2 | |
| SCHEMBL6135990 | 0.81 | ESR1 (0.64) | ESR1ESR2LTA4HSSTR2 | |
| SCHEMBL3714380 | 0.81 | ESR1 (0.64) | ESR1ESR2LTA4HSSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL5256714 | 0.80 | ESR1 (0.66) | ESR1ESR2LTA4HSSTR2CHEK2 | |
| SCHEMBL8337071 | 0.78 | ESR1 (0.43) | ESR1ESR2LTA4HCHEK2 | |
| SCHEMBL8342470 | 0.78 | ESR1 (0.49) | ESR1ESR2LTA4HNPY1R | |
| SCHEMBL6136215 | 0.78 | ESR1 (0.65) | ESR1ESR2LTA4HSSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL6004702 | 0.76 | ESR1 (0.59) | ESR1ESR2LTA4HSSTR2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895989-B1 | 1-[4-(Substituted alkoxy)benzyl] naphthalene compounds having estrogen inhibitory activity | LILLY CO ELI (US) | 2005-05-18 | — | — | EP | claimed |