Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136527 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL14997395 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL6136513 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL6136515 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL4323367 | 0.90 | MEN1 (0.62) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL4156227 | 0.90 | MEN1 (0.62) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL8241511 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL14989384 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL21485090 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL14997394 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951464-B1 | N-(ARYL/HETEROARYLACETYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2005-05-11 | — | — | EP | claimed |
| US-20250288559-A1 | PREP BINDING LIGANDS | POLKU THERAPEUTICS OY (FI) | 2025-09-18 | — | — | US | disclosed |
| EP-4514781-A1 | PREP BINDING LIGANDS | Polku Therapeutics OY (FI) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |
| EP-3283066-B1 | 4-PHENYLBUTYRIC ACID DERIVATIVES | PHENOTEC AG (CH) | 2022-05-11 | — | — | EP | disclosed |
| WO-2019197015-A1 | COMPOSITION COMPRISING 4-PHENYLBUTYRIC ACID DERIVATIVES & OPIOIDS | TRUOG PETER (CH) | 2019-10-17 | — | — | WO | disclosed |
| EP-2599767-A1 | Phenylbutyl-derivatives | Lunamed AG (CH) | 2013-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250288559-A1 | PREP BINDING LIGANDS | PREP, ERAP2, CTSA | SMN1; SMN2 3319/4885HPGD 3255/4885HDAC1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.