Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27560909 | 0.87 | AKR1C3 (0.46) | AKR1C3CYP2C9CYP1A2CYP3A4ALDH1A1 | |
| Phenol SCHEMBL4622241 | 0.86 | CA12 (0.37) | AKR1C3CA12CA1CA2GLA | |
| Phenol SCHEMBL29171775 | 0.86 | AKR1C3 (0.44) | AKR1C3CA12CA1CA2GLA | |
| Phenol SCHEMBL6136517 | 0.85 | AKR1C3 (0.47) | AKR1C3CA12CA1CA2GLA | |
| SCHEMBL23311 | 0.82 | — | — | |
| SCHEMBL10387626 | 0.82 | — | — | |
| SCHEMBL23310 | 0.82 | — | — | |
| Styrene SCHEMBL5665139 | 0.81 | AKR1C3 (0.49) | AKR1C3GLATDP1CYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL9902111 | 0.80 | GRIK1 (0.42) | AKR1C3BACE1ALDH1A1GRIK1GRIK2 | |
| SCHEMBL5072777 | 0.80 | GRIK1 (0.42) | AKR1C3BACE1ALDH1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857468-B1 | Machine for the manufacturing of a dental prosthesis using a composite support shell | BILLET GILLES (FR) | 2005-06-29 | — | — | EP | disclosed |
| US-6635691-B2 | Containing filler and a polymerizable matrix | IVOCLAR VIVADENT AG (LI) | 2003-10-21 | — | — | US | disclosed |
| US-20020040075-A1 | Dental material containing a component which contracts during thermal treatment | IVOCLAR VIVADENT AG. | 2002-04-04 | — | — | US | disclosed |
| US-6287490-B2 | Preparing a mold, filling the mold cavity with a fiber reinforced copolymerizable material comprising an organic matrix and a fiber component embedded within the matrix, pressurizing and curing the reiforced polymerizable material | IVOCLAR AG (LI) | 2001-09-11 | — | — | US | disclosed |
| US-20010001510-A1 | METHOD FOR MANUFACTURING A DENTAL PROSTHESIS | IVOCLAR AG (LI) | 2001-05-24 | — | — | US | disclosed |
| US-6010337-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 2000-01-04 | — | — | US | disclosed |
| US-5951293-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1999-09-14 | — | — | US | disclosed |
| US-5947737-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1999-09-07 | — | — | US | disclosed |
| US-5839900-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1998-11-24 | — | — | US | disclosed |
| EP-0872218-A2 | Method for manufacturing a dental prosthesis | IVOCLAR AG (LI) | 1998-10-21 | — | — | EP | disclosed |
| EP-0857468-A1 | Machine for the manufacturing of a dental prosthesis using a composite support shell | Billet, Gilles (FR) | 1998-08-12 | — | — | EP | disclosed |