Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.50 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.50 |
| ▸ | SDCBP | O00560 | 1/20 | 0.50 |
| ▸ | SDC2 | P34741 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136739 | 1.00 | NR1H4 (0.56) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL16312240 | 0.85 | ELANE (0.54) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL2177216 | 0.84 | POLB (0.63) | MEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL2177223 | 0.84 | POLB (0.63) | MEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL8035990 | 0.84 | POLB (0.63) | MEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL6136552 | 0.84 | MME (0.58) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL14688070 | 0.83 | RECQL (0.54) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL6136338 | 0.82 | RECQL (0.53) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL4415369 | 0.82 | RECQL (0.53) | NR1H4L3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL22764712 | 0.82 | MME (0.64) | NR1H4MEN1KMT2AMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951464-B1 | N-(ARYL/HETEROARYLACETYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2005-05-11 | — | — | EP | claimed |