Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150761 | 0.81 | ESR2 (0.40) | ESR2ESR1 | |
| SCHEMBL6136863 | 0.73 | ESR2 (0.44) | ESR2ESR1 | |
| SCHEMBL6150947 | 0.69 | ESR2 (0.38) | ESR2ESR1 | |
| SCHEMBL6151419 | 0.65 | ESR2 (0.56) | ESR2ESR1 | |
| SCHEMBL2417486 | 0.64 | ESR2 (0.54) | ESR2ESR1 | |
| SCHEMBL12320443 | 0.62 | ESR2 (0.44) | ESR2ESR1 | |
| SCHEMBL2416850 | 0.62 | ESR2 (0.66) | ESR2ESR1 | |
| SCHEMBL2418440 | 0.62 | ESR2 (0.65) | ESR2ESR1 | |
| SCHEMBL2421182 | 0.60 | ESR2 (0.58) | ESR2ESR1 | |
| SCHEMBL2418988 | 0.59 | ESR2 (0.68) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | disclosed |