Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137368 | 0.94 | TSHR (0.31) | — | |
| SCHEMBL5244045 | 0.90 | — | — | |
| SCHEMBL10762384 | 0.83 | — | — | |
| SCHEMBL3045038 | 0.80 | — | — | |
| SCHEMBL9792571 | 0.79 | PTPN7 (0.39) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL6425877 | 0.74 | PTPN7 (0.32) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL2496384 | 0.73 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL9794198 | 0.73 | PTPN7 (0.35) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL10618192 | 0.70 | — | — | |
| SCHEMBL15641128 | 0.69 | PTPN7 (0.45) | PTPN7HMGCRRECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425258-A4 | HYDROXYEICOSENOIC ACID ANALOGS | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1425258-A2 | HYDROXYEICOSENOIC ACID ANALOGS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003024390-A2 | HYDROXYEICOSENOIC ACID ANALOGS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-03-27 | — | — | WO | disclosed |